Fascin antibody

Catalog No. ABIN6568972

The Rabbit Polyclonal anti-Fascin antibody has been validated for WB and IHC. It is suitable to detect Fascin in samples from Human, Mouse and Rat.

Quick Overview for Fascin antibody (ABIN6568972)

Target: Fascin (FSCN1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fascin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Fascin Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human FSCN1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Fascin

Target: Fascin (FSCN1)

Alternative Name: Fascin

Background:

Synonyms: 55 kDa actin bundling protein,55 kDa actin-bundling protein,Actin bundling protein,actin bundling protein,55-KD,FAN 1,FAN1,Fascin 1,Fascin actin bundling protein 1,Fascin,Fascin homolog 1 actin bundling protein (Strongylocentrotus purpuratus),Fascin homolog 1,Fascin,sea urchin,homolog of,1,Fascin1,FLJ38511,FSCN 1,FSCN1,FSCN1,HSN,p55,Singed (Drosophila) like (sea urchin fascin homolog like),Singed drosophila homolog like,Singed like (fascin homolog sea urchin) (Drosophila),Singed like (fascin homolog sea urchin),Singed like protein,Singed,drosophila,homolog of,Singed-like protein,SNL,Strongylocentrotus purpuratus

Background: This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.

Molecular Weight:

Observed_MW: 50kDa, 55kDa

Calculated_MW: 54kDa

Gene ID: 6624

UniProt: Q16658